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Frontiers of Environmental Science & Engineering 2023, Volume 17, Issue 3, doi: 10.1007/s11783-023-1637-9
● Converting xylose to caproate under a low temperature of 20 °C by MCF was verified.
Keywords: Xylose fermentation Caproate Low temperature Bifidobacterium FAB pathway RBO pathway
Frontiers of Environmental Science & Engineering 2021, Volume 15, Issue 6, doi: 10.1007/s11783-021-1433-3
• Short-term effect of the pyridine exposure on the SAD process was investigated.
Keywords: Anammox Inhibition Metabolic pathway Microbial community Pyridine SAD
Zuotao Zhang, Chongyang Wang, Jianzhong He, Hui Wang
Frontiers of Environmental Science & Engineering 2019, Volume 13, Issue 5, doi: 10.1007/s11783-019-1164-x
Keywords: Phenanthrene Anaerobic biodegradation Bacterial populations Archaea populations Metabolic pathway
Metabolomics in human type 2 diabetes research
Jingyi Lu, Guoxiang Xie, Weiping Jia, Wei Jia
Frontiers of Medicine 2013, Volume 7, Issue 1, Pages 4-13 doi: 10.1007/s11684-013-0248-4
Keywords: metabolomics type 2 diabetes metabolic pathway mass spectrometry nuclear magnetic resonance (NMR)
Frontiers of Environmental Science & Engineering 2022, Volume 16, Issue 8, doi: 10.1007/s11783-022-1527-6
• The promoting effects for VFA generation follow the order of APG>SDBS>HTAB.
Keywords: Waste activated sludge (WAS) Volatile fatty acids (VFA) Surfactant types Functional microorganisms Metabolic
Metabolic hypertension: concept and practice
Zhiming Zhu, Peijian Wang, Shuangtao Ma
Frontiers of Medicine 2013, Volume 7, Issue 2, Pages 201-206 doi: 10.1007/s11684-013-0264-4
Keywords: hypertension cardiometabolic risk factors metabolic abnormalities
Jianping Ye
Frontiers of Medicine 2015, Volume 9, Issue 2, Pages 139-145 doi: 10.1007/s11684-015-0377-z
In obesity, chronic inflammation is believed to induce insulin resistance and impairs adipose tissue function. Although this view is supported by a large body of literature, it has been challenged by growing evidence that pro-inflammatory cytokines may favor insulin sensitivity through induction of energy expenditure. In this review article, interleukin 15 (IL-15) is used as a new example to explain the beneficial effects of the pro-inflammatory cytokines. IL-15 is secreted by multiple types of cells including macrophages, neutrophils and skeletal muscle cells. IL-15 expression is induced in immune cells by endotoxin and in muscle cells by physical exercise. Its transcription is induced by transcription factor NF-κB. IL-15 binds to its receptor that contains three different subunits (α, β and γ) to activate JAK/STAT, PI3K/Akt, IKK/NF-κB and JNK/AP1 pathways in cells. In the regulation of metabolism, IL-15 reduces weight gain without inhibiting food intake in rodents. IL-15 suppresses lipogenesis, stimulates brown fat function, improves insulin sensitivity through weight loss and energy expenditure. In human, circulating IL-15 is negatively associated with body weight. In the immune system, IL-15 stimulates proliferation and differentiation of T cells, NK cells, monocytes and neutrophils. In the anti-obesity effects of IL-15, T cells and NK cells are not required, but leptin receptor is required. In summary, evidence from human and rodents supports that the pro-inflammatory cytokine IL-15 may enhance energy expenditure to protect the body from obesity and type 2 diabetes. The mechanism of IL-15 action remains to be fully uncovered in the regulation of energy expenditure.
Keywords: inflammation obesity cytokine energy expenditure insulin resistance
Frontiers of Medicine 2021, Volume 15, Issue 5, Pages 679-692 doi: 10.1007/s11684-021-0866-1
Keywords: metabolic reprogramming potential of electron transfer cell proliferation aerobic glycolysis cancer
Fibroblast growth factor 21: a novel metabolic regulator from pharmacology to physiology
Huating Li, Jing Zhang, Weiping Jia
Frontiers of Medicine 2013, Volume 7, Issue 1, Pages 25-30 doi: 10.1007/s11684-013-0244-8
Keywords: FGF21 metabolism pharmacology physiology clinical relevance
Frontiers of Medicine 2023, Volume 17, Issue 4, Pages 714-728 doi: 10.1007/s11684-022-0959-5
Keywords: FRMD6 lung cancer mTOR pathway
Exploring the methodology and application of clinical pathway in evidence-based Chinese medicine
Sicheng Wang, He Yu, Jianping Liu, Baoyan Liu
Frontiers of Medicine 2011, Volume 5, Issue 2, Pages 157-162 doi: 10.1007/s11684-011-0128-8
Keywords: evidence-based medicine clinical pathway methodology concept technical difficulty
Metformin and metabolic diseases: a focus on hepatic aspects
Juan Zheng,Shih-Lung Woo,Xiang Hu,Rachel Botchlett,Lulu Chen,Yuqing Huo,Chaodong Wu
Frontiers of Medicine 2015, Volume 9, Issue 2, Pages 173-186 doi: 10.1007/s11684-015-0384-0
Keywords: metformin diabetes hepatic steatosis inflammatory response insulin resistance
Jichun Yang, Kaiyue Jin, Jiajun Xiao, Jing Ma, Duan Ma
Frontiers of Medicine 2017, Volume 11, Issue 3, Pages 403-409 doi: 10.1007/s11684-017-0522-y
Tissue factor pathway inhibitor (TFPI) is the main inhibitor of tissue factor-mediated coagulation
Keywords: arterial thrombosis conditional knockout mice tissue factor pathway inhibitor vascular smooth muscle
Water-dispersible nano-pollutions reshape microbial metabolism in type-specific manners: A metabolic
Frontiers of Environmental Science & Engineering 2022, Volume 16, Issue 9, doi: 10.1007/s11783-022-1548-1
• Water-dispersible nano-pollutions exhibit type-specific toxic effects on E. coli.
Keywords: Nano-toxicity Nano-plastics Quantum dots Microbial metabolite Metabolic dysregulation
Xiaokun Li
Frontiers of Medicine 2019, Volume 13, Issue 5, Pages 511-530 doi: 10.1007/s11684-019-0711-y
Keywords: FGF19 FGF21 FGF23 FGFR metabolism endocrine Klotho
Title Author Date Type Operation
Low-temperature caproate production, microbial diversity, and metabolic pathway in xylose anaerobic fermentation
Journal Article
denitrification system with short-term pyridine exposure: Process capability, inhibition kinetics and metabolic
Journal Article
biodegradation with four kinds of electron acceptors enriched from the same mixed inoculum and exploration of metabolic
Zuotao Zhang, Chongyang Wang, Jianzhong He, Hui Wang
Journal Article
Metabolomics in human type 2 diabetes research
Jingyi Lu, Guoxiang Xie, Weiping Jia, Wei Jia
Journal Article
New insights into different surfactants’ impacts on sludge fermentation: Focusing on the particular metabolic
Journal Article
Metabolic hypertension: concept and practice
Zhiming Zhu, Peijian Wang, Shuangtao Ma
Journal Article
Beneficial metabolic activities of inflammatory cytokine interleukin 15 in obesity and type 2 diabetes
Jianping Ye
Journal Article
electron transfer and its application in dictating routes of biochemical processes associated with metabolic
Journal Article
Fibroblast growth factor 21: a novel metabolic regulator from pharmacology to physiology
Huating Li, Jing Zhang, Weiping Jia
Journal Article
FERM domain-containing protein FRMD6 activates the mTOR signaling pathway and promotes lung cancer progression
Journal Article
Exploring the methodology and application of clinical pathway in evidence-based Chinese medicine
Sicheng Wang, He Yu, Jianping Liu, Baoyan Liu
Journal Article
Metformin and metabolic diseases: a focus on hepatic aspects
Juan Zheng,Shih-Lung Woo,Xiang Hu,Rachel Botchlett,Lulu Chen,Yuqing Huo,Chaodong Wu
Journal Article
Endogenous tissue factor pathway inhibitor in vascular smooth muscle cells inhibits arterial thrombosis
Jichun Yang, Kaiyue Jin, Jiajun Xiao, Jing Ma, Duan Ma
Journal Article
Water-dispersible nano-pollutions reshape microbial metabolism in type-specific manners: A metabolic
Journal Article